David Main, BSc, MBA

President and CEO, Notch Therapeutics – Independent Board member

David is President and Chief Executive Officer of Notch Therapeutics. Previously, as Chairman and CEO of Aquinox Pharmaceuticals, a company he co-founded in 2006, David oversaw the advancement of the company’s lead product from target validation through Phase 3 clinical trials. He also led the transition of Aquinox from a private company to a Nasdaq-listed public company with approximately $300 million raised in equity capital and then completed the successful merger of Aquinox with Neoleukin Therapeutics. Prior to his leadership of Aquinox, David served as President and CEO of INEX Pharmaceuticals and as a Vice President of QLT. He formerly served as the Chair of LifeSciences BC (formerly BC Biotech), BIOTECanada, and Accel-Rx as well as a Director of BIO.org. David began his career as a licensed pharmacist at the Royal Columbian Hospital in New Westminster, B.C. He received a BSc in pharmacy and an MBA from the University of British Columbia.

the Management team

CEO & Chairman

Head of Medicinal Chemistry

Head of Biology & Pharmacology

Scientific Founder

Director of Research 1st class at the CNRS, directing the multidisciplinary Chemistry & Biology, Modeling & Immunology for Therapy (CBMIT) team within the CNRS and the Université de Paris

Board Of Directors​

President and CEO, Notch Therapeutics - Independent Board member

CEO & Chairman

CEO, Domain Therapeutics - Board member

Founder & CEO of Parthenon Therapeutics - Board member

Managing partner, Kurma Life Sciences Partners - Board member

Principal, Kurma Life Sciences Partners - Board member

Managing Partner & Co-Founder, Fountain Healthcare Partners - Board member

Senior Associate, Fountain Healthcare Partners - Board observer

Scientific and Clinical Advisors

Chairman of the Scientific Advisory Board

Stanford Univ, School of Med (US) | Rheumatology-SLE

John Hopkins Medicine (US) | Rheumatology-SLE

UMC Amsterdam (NL) | Rheumatology-SLE

Director of Research 1st class at the CNRS, directing the multidisciplinary Chemistry & Biology, Modeling & Immunology for Therapy (CBMIT) team within the CNRS and the Université de Paris

Professor of Target and Systems Biochemistry at the Faculty of Science of the Vrije Universiteit Amsterdam

Gardiner Professor of Biochemistry, and Deputy Head of the College of Medical, Veterinary and Life Sciences at the University of Glasgow

Chief Executive Officer of the Institute for Research in Immunology and Cancer at the University of Montréal